HEAL Initiative: Pain Management Effectiveness Research Network: Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

Summary

The NIH HEAL (Helping to End Addiction Long-term) Initiative is seeking applications for a Pain Management Effectiveness Research Network cooperative agreement. The award mechanism is a UG3/UH3 phased cooperative agreement requiring a clinical trial. The UG3 phase covers clinical trial planning and the UH3 phase covers implementation. This funding opportunity is aimed at advancing pain management research through rigorous clinical trials as part of the broader federal HEAL Initiative to address the opioid crisis and improve pain treatment.

What they want

How they evaluate

Risks & flags

• Opportunity is listed as 'forecasted' — full solicitation details, eligibility requirements, and due dates are not yet published, limiting competitor preparation time once the full RFA is released
• RFA number (RFA-NS-25-031) suggests this is issued through a specific NIH institute (NINDS), which may narrow the competitive pool to researchers with established neurological/pain science track records