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NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)

US · US National Institutes of Health (NIH) — National Institute on Deafness and Other Communication Disorders (NIDCD) grant open #PAR-25-445
Response due Oct 03, 2026 · 00:00 UTC

Summary

The National Institute on Deafness and Other Communication Disorders (NIDCD), a component of the National Institutes of Health (NIH), is offering a Clinical Research Center Grant (P50) that optionally includes clinical trials. The P50 mechanism supports integrated, multidisciplinary research center programs focused on NIDCD's mission areas, which include hearing, balance, smell, taste, voice, speech, and language disorders. This is a program announcement (PAR-25-445) open for submissions over a roughly 12-month window. Applicants may propose clinical trials as part of their center grant application.

What they want

Applicants are invited to submit research center grant proposals (P50 mechanism) addressing clinical research within NIDCD's mission areas (hearing, balance, smell, taste, voice, speech, and/or language). Proposed projects may optionally include clinical trials. Awards support integrated, collaborative, multidisciplinary research programs organized around a central theme relevant to communication disorders.
Technical requirements
  • P50 Research Center Grant mechanism
  • Clinical trial inclusion is optional
  • Must align with NIDCD mission areas: hearing, balance, smell, taste, voice, speech, or language
  • Multidisciplinary, integrated research center structure required

How they evaluate

  • Scientific and technical merit (standard NIH peer review criteria: Significance, Investigators, Innovation, Approach, Environment)
  • Relevance to NIDCD mission
  • Overall impact score from NIH Study Section review
Submission: Grants.gov electronic submission portal (standard NIH application package via Grants.gov)

Eligibility & certifications

SAM.gov registration (for institutional applicants)NIH eRA Commons registrationInstitutional compliance with HHS human subjects regulations if clinical trials included

Risks & flags

  • Extremely long open window (~12 months) with rolling submissions is standard for NIH PARs — not a red flag in isolation
  • No dollar figures or award ceiling disclosed in the synopsis — budget details not evaluable from this record
  • Highly specialized scope (NIDCD mission areas only) limits eligible applicant pool to institutions with relevant communication disorders research infrastructure

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541714
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

NIDCD Clinical Research Center Grant (P50 …
Due Oct 03
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