BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)

US · MD National Institutes of Health (NIH) grant open #RFA-NS-25-018

Response due Jun 16, 2026 · 00:00 UTC

Summary

This NIH BRAIN Initiative funding opportunity (RFA-NS-25-018) solicits R01 research grant applications focused on developing new technologies and novel approaches for recording and modulating activity in the nervous system. Clinical trials are explicitly excluded from this mechanism. The opportunity is issued by the National Institutes of Health under the Department of Health and Human Services and is open for applications from September 2024 through June 2026.

What they want

Technical requirements

Clinical trials are not allowed under this funding mechanism
Must align with BRAIN Initiative goals for recording and modulation in the nervous system
R01 grant mechanism applies

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

No dollar value or award ceiling stated — budget expectations unclear
Long open window (Sept 2024 – June 2026) may mask rolling review cycles with unstated internal deadlines

Market context

inferred from NAICS

Professional, Scientific & Technical Services

NAICS 541714

US market size: $2.0T
Typical award: $25K – $50M

Typical buyers

All federal civilianDoDStates

Commonly required

8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

BRAIN Initiative: New Technologies and Nov…

Due Jun 16

Onboard ↗