Summary
Patients opting for TMJ disc removal face issues due to the absence of FDA-approved replacements, leading to bone-to-bone contact and subsequent joint problems. Autografts, like dermis-fat grafts, typically resorb within a year. Our goal is a secure disc replacement alternative. Previous studies demonstrated rapid transformation of an acellular ECM scaffold into TMJ disc-like tissue in canine and porcine models. The canine model, chosen for its hinge- socket preventing implant migration, lacks human-like motions, and pig models have access issues. Introducing the goat model, with human-like ac