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Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)

US National Institutes of Health (NIH) grant open #PAR-27-081
Response due Mar 05, 2027 · 00:00 UTC

Summary

This NIH funding opportunity (PAR-27-081) solicits R01 research grant applications focused on the discovery of in vivo chemical probes for the nervous system. Clinical trials are explicitly excluded from this mechanism. The program is administered by the National Institutes of Health under the Department of Health and Human Services. Applicants are expected to propose basic or translational research developing chemical tools to study nervous system biology in living systems.

What they want

Technical requirements
  • Research must focus on discovery of in vivo chemical probes
  • Scope must be limited to the nervous system
  • Clinical trials are not allowed under this funding mechanism
  • Must conform to NIH R01 grant requirements

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

  • Extremely broad open-to-close window (~10 months) is standard for NIH program announcements and does not indicate wiring, but scope is highly specialized (in vivo chemical probes + nervous system only), which may limit the eligible applicant pool significantly

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541714
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Discovery of in vivo Chemical Probes for t…
Due Mar 05
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