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Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)

US · MD National Institutes of Health (NIH) grant open #PAR-25-311
Response due Nov 15, 2027 · 00:00 UTC

Summary

The NIH is soliciting applications under PAR-25-311 to leverage existing network infrastructure to conduct innovative research focused on women, children, pregnant and lactating women, and persons with disabilities. The funding mechanism is a UG3/UH3 cooperative agreement, which is a phased award structure (planning/milestone-driven phase followed by implementation). Clinical trials are optional under this announcement. The opportunity is open for multiple years, accepting applications through November 2027.

What they want

Applicants must propose to leverage existing network infrastructure to design and conduct innovative research benefiting one or more of the following underrepresented or underserved populations: women, children, pregnant and lactating women, and/or persons with disabilities. The award mechanism is a two-phase UG3/UH3 cooperative agreement: the UG3 phase involves planning and milestone achievement, and the UH3 phase involves full implementation of the research. Clinical trials are permitted but not required. Applications are accepted on a rolling basis through the close date of November 15, 2027.
Technical requirements
  • Must leverage existing network infrastructure
  • Research must focus on women, children, pregnant/lactating women, or persons with disabilities
  • Two-phase cooperative agreement structure: UG3 (planning/milestones) and UH3 (implementation)
  • Clinical trial component is optional

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

  • Multi-year rolling open window (2024–2027) suggests programmatic flexibility but may favor established NIH network partners with pre-existing infrastructure relationships
  • Requirement to 'leverage existing network infrastructure' may implicitly favor applicants already embedded in NIH-funded research networks

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Leveraging Network Infrastructure to Condu…
Due Nov 15
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