Summary
Project Summary There are several ophthalmological diseases and ailments that perturb the normal water content or hydration levels of the corneal layer. Among these, Fuchs’ dystrophy, keratoconus, and elevated intraocular pressure (IOP) - a common cause of glaucoma, to name a few examples, can have a drastic impact on the patients’ vision. The work outlined in this proposal will develop terahertz spectroscopy instruments that enable spatially and spectrally resolved measurements across the entire corneal surface to map hydration gradients of the tissue in various disease models. Specifically,