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Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)

US National Institutes of Health (NIH) grant open #PAR-25-207
Response due Jan 07, 2028 · 00:00 UTC

Summary

This NIH funding opportunity (PAR-25-207) solicits R01 grant applications for effectiveness trials focused on post-acute care interventions and services designed to optimize longer-term patient outcomes. Applicants must propose a clinical trial as a required component. The opportunity is issued by the National Institutes of Health (HHS-NIH) and remains open for multiple submission cycles through early 2028. It targets researchers studying how post-acute care strategies can improve recovery and long-term health outcomes.

What they want

Fund and conduct effectiveness (R01) clinical trials evaluating post-acute care interventions and services. Research must be designed to measure and optimize longer-term outcomes for patients receiving post-acute care. A clinical trial component is required for all applications submitted under this notice of funding opportunity (NOFO).
Technical requirements
  • Clinical trial design is required for all submitted applications
  • Research must focus on post-acute care interventions and services
  • Studies must be oriented toward measuring longer-term patient outcomes

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

  • No dollar value or budget ceiling specified — award size is indeterminate
  • Rolling/multi-year submission window (through Jan 2028) makes competitive landscape difficult to assess
  • Requirement for a clinical trial may narrow eligible applicants significantly

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541714
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Effectiveness Trials for Post-Acute Interv…
Due Jan 07
Onboard