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Single-cell Analysis of Normal and Perturbed Dynamic and Spatial Biological Systems

US National Institute of Environmental Health Sciences grant open #nih-1ZIAES103350-06

Summary

The aim of this project is to utilize network models as a powerful framework to investigate the complexity, spatial organization and dynamics of biological processes during development from genetic, environmental and pharmacological perturbations or exposures. In systems biology, network models provide a comprehensive understanding of the interconnections and dependencies within biological systems. They enable us to predict system behavior, build reference maps, identify potential drug targets, and discover disease biomarkers. In the last three years, we developed and published at least six ma

Single-cell Analysis of Normal and Perturb…
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