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Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

US · US National Institutes of Health / National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) grant open #PAR-25-091
Response due Jan 07, 2028 · 00:00 UTC

Summary

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a component of NIH/HHS, is offering a limited competition small grant program (R03 mechanism) for early-career researchers who are current or recent recipients of NIDDK mentored career development awards (K01, K08, K23, or K25). The program is designed to provide supplemental research funding to support these investigators as they transition toward independence. Clinical trials are optionally permitted under this funding opportunity. The opportunity is posted as a Program Announcement with Review (PAR-25-091) and remains open for multiple submission cycles through early 2028.

What they want

This is a federal grant funding opportunity (not a procurement contract) issued by NIH/NIDDK under announcement number PAR-25-091. Eligible applicants are individuals who currently hold or have recently held an NIDDK-funded mentored career development award (K01, K08, K23, or K25). Awardees will conduct small research projects using the R03 grant mechanism. Clinical trials are optionally permitted. The program is a limited competition, restricting eligibility to the defined pool of K-award recipients. The opportunity opened January 10, 2025, and accepts applications through January 7, 2028.
Technical requirements
  • Applicant must be a current or recent NIDDK K01, K08, K23, or K25 award recipient
  • R03 small grant mechanism applies
  • Clinical trials optionally permitted

How they evaluate

  • NIH peer review (scientific merit)
  • Significance
  • Innovation
  • Approach
  • Investigator qualifications
  • Environment
Submission: Electronic submission via Grants.gov and NIH eRA Commons

Eligibility & certifications

Active or recent NIDDK K01/K08/K23/K25 career development award recipientInstitutional registration in Grants.gov and NIH eRA Commons

Risks & flags

  • Limited competition restricts eligibility exclusively to NIDDK K-award recipients — by design, this narrows the applicant pool significantly
  • No dollar values or award sizes disclosed in the posted synopsis
  • Multi-year open window (2025–2028) with rolling submissions may obscure specific deadline competition dynamics

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Limited Competition: Small Grant Program f…
Due Jan 07
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