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TOF-PET with high-efficiency TlCl crystals

US National Institute of Biomedical Imaging and Bioengineering grant open #nih-5R01EB034062-04

Summary

Summary Time-of-flight positron emission tomography is a very effective nuclear imaging modality for the diagnosis and staging of a range of pathologies such as cancer, cardiovascular diseases, or musculoskeletal disorders. Commercial TOF-PET scanners currently employ lutetium-(yttrium)-oxyorthosilicate (L(Y)SO) crystal detectors coupled to silicon photomultipliers (SiPMs) to achieve coincidence time resolutions (CTR) between 200-500 ps full width at half maximum (FWHM). High production costs of L(Y)SO crystals and their intrinsic radiation background are currently hindering the evolution and

TOF-PET with high-efficiency TlCl crystals
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