Summary
PROJECT SUMMARY Low-resource settings have a high burden of Neisseria gonorrhoeae infection, but insufficient laboratory infrastructure for diagnostic tests and antimicrobial susceptibility determination, leading to syndromic management, which misses a high proportion of cases and results in the overuse of antibiotics. Together, those factors contribute to driving the emergence of antimicrobial resistance (AMR), a global public health threat. Two novel strategies can combine to address those challenges. First, the use of CRISPR-based technology permits the development of low-cost, point-of-car