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Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

US · US National Institutes of Health (NIH) grant open #PAR-25-145
Response due Jan 07, 2028 · 00:00 UTC

Summary

This NIH funding opportunity (PAR-25-145) solicits R01 research grant applications focused on the clinical characterization of adverse sequelae caused by cancer therapies and the development of mechanism-based interventional strategies to address them. Applicants may optionally include clinical trials as part of their proposed research. The opportunity is issued by the National Institutes of Health (HHS-NIH) and remains open for submissions through early 2028, indicating a multi-cycle, standing Program Announcement with Review (PAR).

What they want

Technical requirements
  • Clinical trial inclusion is optional (R01 Clinical Trial Optional designation)
  • Must address cancer therapy-induced adverse sequelae
  • Must include mechanism-based interventional strategies
  • Must conform to NIH R01 grant application requirements under PAR-25-145

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

  • No dollar values or award sizes disclosed in the posted synopsis — budget expectations cannot be assessed
  • Long open window (Nov 2024 – Jan 2028) suggests rolling/multiple submission cycles; individual deadlines not specified in this record

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Clinical Characterization of Cancer Therap…
Due Jan 07
Onboard