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NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)

US · MD · Bethesda National Institutes of Health – National Eye Institute (NEI) grant open #PAR-25-357
Response due Oct 16, 2027 · 00:00 UTC

Summary

The National Eye Institute (NEI), part of the National Institutes of Health (NIH), is offering an R21 research grant mechanism for vision-related secondary data analysis. The opportunity is restricted to secondary data analysis projects and explicitly excludes clinical trials. It is a federal grant solicitation (Program Announcement/Request) aimed at supporting exploratory/developmental research leveraging existing datasets in vision science. The opportunity has a multi-year open window, running from January 2025 through October 2027.

What they want

Applicants must propose secondary data analysis research related to vision. Clinical trials are not allowed under this funding opportunity. The R21 mechanism supports exploratory and developmental research projects. Researchers must use existing datasets to advance knowledge in vision-related fields under the purview of the National Eye Institute (NEI). No new primary data collection or clinical trial activity is permitted.
Technical requirements
  • Secondary data analysis only — no primary data collection permitted
  • Clinical trials are explicitly not allowed
  • Must align with NEI research mission and vision-related topics
  • R21 exploratory/developmental research mechanism applies

How they evaluate

Submission: Grants.gov electronic submission portal

Risks & flags

  • Ultra-long open window (nearly 3 years) suggests rolling submission with multiple due dates not captured in this synopsis — actual submission deadlines may differ from close date
  • Restriction to secondary data analysis may narrow the applicant pool significantly
  • No dollar values or award ranges stated — budget limits typical of R21 (~$275K direct costs over 2 years) are implied by NIH norms but not confirmed in this text

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

NEI Research Grant for Vision-Related Seco…
Due Oct 16
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