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Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)

US · US National Institutes of Health (NIH) grant open #PAR-25-079
Response due Jan 07, 2027 · 00:00 UTC

Summary

The National Institutes of Health (NIH) is soliciting R01 grant applications under Program Announcement PAR-25-079 to support Academic-Industrial Partnerships (AIP) aimed at translating and validating in vivo imaging systems. The program encourages collaboration between academic researchers and industry partners to advance biomedical imaging technologies from research into clinical or applied settings. Clinical trials are optional under this funding opportunity. The announcement opened in November 2024 and accepts applications through January 2027.

What they want

Applicants must form academic-industrial partnerships to translate and validate in vivo imaging systems. Projects may optionally include clinical trials. The work involves advancing imaging technologies through collaborative research between academic institutions and industry, with the goal of moving imaging innovations toward practical, validated, in vivo applications. Proposals must conform to NIH R01 grant requirements as outlined in PAR-25-079.
Deliverables
  • R01 grant application per NIH PAR-25-079 requirements
  • Research progress reports as required by NIH
  • Validated in vivo imaging system data/findings
  • Publications and/or clinical trial results (if applicable)
Technical requirements
  • Partnership must involve both an academic institution and an industry partner
  • Research must focus on translation and validation of in vivo imaging systems
  • Clinical trials are optional but permissible
  • Must comply with NIH R01 grant application guidelines
Key personnel
  • Principal Investigator (academic)
  • Industry partner representative/co-investigator

How they evaluate

  • Scientific and technical merit (NIH peer review criteria)
  • Innovation and significance of imaging technology
  • Approach and rigor of validation methods
  • Qualifications of academic and industry team
  • Potential for clinical translation
Submission: Grants.gov electronic submission per NIH R01 application requirements

Eligibility & certifications

SAM.gov registration (for institutional applicants)NIH institutional assurances (IRB, IACUC as applicable)Compliance with NIH human subjects and clinical trial policies

Risks & flags

  • Long open window (over 2 years) suggests rolling/multiple submission cycles rather than a single competitive award — not a traditional RFP
  • No dollar value or award ceiling stated, making budget competitiveness assessment difficult
  • Requirement for pre-existing academic-industrial partnership may favor established teams with prior industry relationships

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541714
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Academic-Industrial Partnerships (AIP) to …
Due Jan 07
Onboard ↗