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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)

US · US National Institutes of Health (NIH) grant open #PA-25-424
Response due May 07, 2028 · 00:00 UTC

Summary

The National Institutes of Health (NIH) is offering the Ruth L. Kirschstein NRSA Individual Senior Fellowship (F33) to support experienced scientists who wish to make major changes in the direction of their research careers or to broaden their scientific background through advanced training. This is a parent funding opportunity announcement (FOA) covering multiple NIH institutes and centers. The program provides fellowship support for senior-level researchers seeking advanced mentored research training experiences. The opportunity is open from June 2025 through May 2028, spanning multiple application cycles.

What they want

The F33 fellowship mechanism funds individual senior fellowship awards for experienced scientists (typically those who have already earned a doctoral degree and have substantial research experience) who are seeking to make significant career changes or broaden their scientific expertise through advanced mentored research training. Applicants must identify a sponsoring institution and mentor. The award supports stipends, tuition/fees, and institutional allowances for the fellowship training period. This is a Parent FOA, meaning it is a general-purpose announcement applicable across participating NIH institutes and centers unless a more specific FOA is available.
Deliverables
  • Completion of advanced mentored research training
  • Progress reports to NIH
  • Final fellowship summary report
Technical requirements
  • Applicant must be an experienced scientist with a doctoral-level degree
  • Must identify a sponsoring institution and qualified mentor
  • Training plan must demonstrate significant career change or broadening of scientific background
  • Must comply with NIH NRSA terms and conditions

How they evaluate

  • Scientific merit of the proposed training
  • Qualifications and potential of the applicant
  • Quality of the training environment and mentor
  • Appropriateness of the training plan for career development goals
  • Relevance to NIH mission and participating institute priorities
Submission: Grants.gov electronic submission portal (NIH eRA Commons)

Eligibility & certifications

SAM registration (for sponsoring institution)NIH eRA Commons registration (applicant and institution)

Risks & flags

  • Extremely long open window (nearly 3 years) is standard for NIH Parent FOAs — not a red flag per se, but indicates a rolling/recurring announcement rather than a discrete competitive procurement
  • Minimal descriptive detail in the synopsis; full eligibility and scoring criteria require review of the complete FOA on NIH Guide

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541714
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Ruth L. Kirschstein National Research Serv…
Due May 07
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