Summary
Abstract The opioid epidemic represents a major public health crisis in the U.S. Although medications such as buprenorphine are the current gold standard treatment for individuals diagnosed with opioid use disorder (OUD), a significant proportion of patients return to illicit opioid use and/or discontinue treatment prematurely. Moreover, the co-occurrence of a psychiatric condition is one important contributor to poor treatment outcomes. Recognizing and responding adaptively to substance-related and personal cues that can trigger both craving and substance use behaviors is a crucial behavioral