Summary
This project aims to understand the genetic, neuronal, and physiological underpinnings of reproductive behaviors in Drosophila to gain insights into mental health and disease.
Genes underlying reproductive behavior physiology and neuronal development
US · IL
National Institutes of Health (NIH) / National Institute of General Medical Sciences (NIGMS)
grant
awarded
#nih-5R35GM145282-04
What they want
The research will utilize Drosophila as a model system to analyze complex behaviors at the level of genes, gene regulatory networks, neurons, circuit structure, and physiology. It will leverage known sex-specific master regulatory transcription factors to identify and manipulate neurons underlying reproductive behaviors, perform neuron-specific mutational studies to discover gene functions, and examine sex-specific neuronal development and modification by adult experiences. The work will build on 15 years of NIGMS-funded research.
Deliverables
- Insights into complex behaviors
- Understanding of genes underlying reproductive behavior physiology and neuronal development
Technical requirements
- Cutting-edge molecular-genetic tools
- Genomic tools
- Proteomic tools
- Behavioral tools
- Microscopy tools
Risks & flags
Incumbent: The researcher's laboratory (15-year NIGMS funded research program)
