Novel Spatial-Motor Approaches Targeting Post-Stroke Spatial Neglect and Gait Deficits

The project seeks to generate data supporting novel motor spatial retraining approaches to enhance rehabilitation of spatial neglect (SN) and gait performance in post-stroke individuals. Specifically, it will evaluate the effects of combining PAT and electrical stimulation (Aim 1), as well as PAT and gait training (Aim 2), on Aiming SN and gait performance. Hypotheses include that adding stimulation to the neglected upper limb during PAT will induce larger improvements in Aiming SN and greater generalization to gait performance, and that gait training with stimulation to the left lower limb preceded by PAT will induce larger improvements in gait performance than gait training with stimulation alone. The work will inform future design of new and targeted treatment protocols for evidence-based rehabilitation.