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NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)

US · MD · Bethesda National Institutes of Health – National Institute on Deafness and Other Communication Disorders (NIDCD) grant open #RFA-DC-25-002
Response due Oct 12, 2027 · 00:00 UTC

Summary

The National Institute on Deafness and Other Communication Disorders (NIDCD), a component of the National Institutes of Health (NIH), is soliciting R01 research grant applications focused on translating basic research findings into clinical practice. The opportunity is open to clinical trial research or non-clinical trial research (clinical trial optional). The funding opportunity (RFA-DC-25-002) spans a multi-year window from late 2024 through October 2027, reflecting a standing/recurring announcement typical of NIH Research Project Grant mechanisms.

What they want

Applicants must propose research projects that bridge basic science discoveries and their translation into clinical applications relevant to NIDCD's mission areas, which include hearing, balance, smell, taste, voice, speech, and language. The R01 mechanism supports discrete, specified, circumscribed projects. Clinical trials are optional but permissible under this announcement. Awardees are expected to conduct the proposed research, produce scientific findings, and report results in accordance with NIH reporting requirements.
Deliverables
  • Research project execution per approved aims
  • NIH progress reports (annual)
  • Final research report
  • Clinical trial registration (if applicable)
  • Publication of results per NIH public access policy
Technical requirements
  • Research must align with NIDCD mission areas (hearing, balance, smell, taste, voice, speech, language)
  • Must demonstrate translational bridge from basic science to clinical application
  • Clinical trials must comply with NIH clinical trial policies if included
  • Applications must follow NIH R01 format and page limits
Key personnel
  • Principal Investigator (PI) with relevant research expertise
  • Co-Investigators as applicable
  • Clinical trial coordinator (if clinical trial included)

How they evaluate

  • Scientific and technical merit (peer review by NIH study section)
  • Significance and innovation
  • Approach and rigor
  • Investigator qualifications and environment
  • Programmatic relevance to NIDCD mission (secondary review by NIDCD Council)
Submission: Electronic submission via Grants.gov and NIH ASSIST/eRA Commons

Eligibility & certifications

SAM.gov / Grants.gov registrationInstitutional assurances (IRB approval if human subjects involved)IACUC approval if animal subjects involvedNIH human subjects training certifications (as applicable)

Risks & flags

  • No explicit dollar caps or award limits stated in the synopsis — applicants should consult the full RFA for budget constraints
  • Multi-year open window (2024–2027) with a single RFA number is typical for NIH but worth confirming multiple submission dates exist within the window
  • Minimal detail provided in synopsis — full RFA text should be reviewed before committing resources to an application

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

NIDCD Research Grants for Translating Basi…
Due Oct 12
Onboard ↗