Laboratories to Optimize Digital Health (R01 Clinical Trial Required)

Summary

This is a National Institutes of Health (NIH) funding opportunity announcement (FOA) under the R01 mechanism requiring a clinical trial. It invites research proposals focused on optimizing digital health technologies and interventions through laboratory-based and/or clinical trial methodologies. The opportunity is a broad, standing announcement open for multiple years (2024–2028), suggesting a programmatic priority at NIH to fund iterative, rigorous studies that improve the efficacy and implementation of digital health tools. Applicants must include a clinical trial component in their proposed research.

What they want

How they evaluate

• Scientific and technical merit (reviewed by NIH study section)
• Significance and innovation of proposed digital health research
• Approach rigor and feasibility of clinical trial design
• Investigators' qualifications and team expertise
• Environment and available resources

Eligibility & certifications

Risks & flags

• No dollar value or budget cap specified — difficult to assess award size competitiveness
• Multi-year open window (2024–2028) with rolling submissions typical of NIH PARs — not wired for a single awardee but highly competitive
• Clinical trial requirement narrows eligible applicant pool to institutions with trial infrastructure