Summary
PROJECT SUMMARY ABSTRACT Infections by Salmonella present a constant threat to human health in our country and throughout the world. Yet, our progress toward controlling salmonellosis has been largely fruitless; antibiotics are rarely warranted, and, when used, frequently fail due to resistant strains. To control this important foodborne pathogen, it is essential to understand the means by which it colonizes and induces disease. Chemical signals of the intestine, including those produced by both the animal host and the microbiota, can repress Salmonella virulence by reducing its ability to inv
