Summary
The project aims to formalize and expand central data management and biostatistical resources for the Columbia Alzheimer’s Disease Research Center (ADRC), ensuring data accuracy, security, and accessibility for research initiatives.
Data Core
US · IL
Columbia Alzheimer’s Disease Research Center (NIH RePORTER)
grant
awarded
#nih-2P30AG066462-06
What they want
The Database Management and Statistical (DMS) Core will maintain a central data resource for all cores, provide procedures for data accuracy, integrity, and security, and facilitate access to clinical, genetics, biofluids, neuropathological, and imaging data. It will ensure timely data submission to NACC, coordinate data sharing, and process requests for data and biological resources. The DMS Core will also serve as a resource for research design, statistical analysis, planning, and training for other cores and Alzheimer’s research initiatives. Additionally, it will collaborate with the ORE and Clinical Cores to enhance web-based systems for recruitment into clinical trials, inclusion of NIH-designated high-risk populations, and streamlining autopsy data acquisition and submission.
Deliverables
- Central data resource for all cores' information
- Well-defined procedures for data accuracy, integrity, and security
- Mechanisms for maintaining data accuracy, integrity, and security
- Facilitated access to Center resources (clinical, genetics, biofluids, neuropathological, imaging data)
- Timely submission of data to NACC
- Coordinated data sharing (processing and fulfillment of requests)
- Research design support
- Statistical analysis support
- Planning support
- Training support
- Enhanced web-based systems to support recruitment into clinical trials and observational studies
- Enhanced web-based systems to facilitate inclusion of NIH-designated high-risk populations
Technical requirements
- Enhancement of existing web-based systems
