Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)

Summary

The National Center for Complementary and Integrative Health (NCCIH), part of NIH/HHS, is soliciting applications for a Clinical Coordinating Center to support multi-site investigator-initiated clinical trials of natural products. The funding mechanism is a collaborative UG3/UH3 award, which involves a phased trial design requiring a clinical trial. This is a federal grant opportunity posted on Grants.gov targeting research institutions capable of coordinating complex, multi-site clinical research on natural products.

What they want

How they evaluate

• Scientific and technical merit reviewed by NIH Study Section
• Innovation and significance of natural products clinical trial
• Approach and feasibility of multi-site coordination
• Qualifications and experience of investigative team
• Environment and institutional support

Risks & flags

• No dollar value disclosed, making budget competitiveness difficult to assess
• UG3/UH3 phased mechanism is highly specific and limits eligible applicants to those experienced with NIH cooperative agreement trial structures
• Long open window (Oct 2024 – Jul 2026) with rolling submissions may reflect difficulty attracting qualified applicants or ongoing program with existing relationships