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Enhancing Solid Tumor lmmunotherapy with Targeted siRNA Delivery

US National Cancer Institute grant open #nih-1R43CA306686-01

Summary

Abstract To address the significant challenges of immunotherapy for solid tumors, Absco Therapeutics (AbscoTx) has developed a novel intratumoral delivery system utilizing the Oncolymer™ platform. The need for new effective approaches to deliver therapeutics into tumors and activate the potential of immunotherapy for solid tumors is particularly evident in microsatellite instability-low (MSI-low) cancers, such as most colorectal carcinomas where immune-checkpoint inhibitors show efficacy in less than 5% of patients. The Oncolymer platform can revolutionize tumor therapy by enabling sustained,

Enhancing Solid Tumor lmmunotherapy with T…
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