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The Role of Prenatal Cannabis Exposure in Reward-related Neural Circuitry and Psychotic-like Experiences in Youth

US National Institute on Drug Abuse grant open #nih-5F31DA060068-03

Summary

PROJECT SUMMARY Cannabis use is becoming increasingly common in the US, and past-month use among pregnant women increased by almost 60% from 2003 to 2019. Despite increasingly permissive legislation, our knowledge of the behavioral and neurobiological consequences of prenatal exposure to cannabis and delta-9- tetrahydrocannabinol (THC) lags behind. Hazardous cannabis use has been linked to psychosis onset and psychotic-like experiences throughout the lifespan, and both cannabis use and psychosis have overlapping neural foundations in reward circuitry. However, the effects of prenatal cannabis

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