Longitudinal EEG and Environmental Trajectories Leading to ADHD and Disruptive Behaviors from Infancy to Preschool

The study will leverage an existing NINDS-funded sample of low-resourced, racially and ethnically diverse infants from an urban primary pediatric care clinic, for whom EEG, developmental, and environmental data are already being collected longitudinally from 4- to 24-months old. The current investigation will collect additional EEG and ADHD/DB-focused measures at a 3- or 4-year well-child visit to assess preschool outcomes. The first aim is to characterize neurodevelopmental trajectories using repeated EEG. The second aim is to integrate parent survey data and medical record abstraction on social determinants of health (e.g., socioeconomic status, caregiver well-being, access to basic needs) into longitudinal models of brain development and behavioral regulation. Results will inform the development of scalable tools for early identification and targeted preventative interventions.