Summary
Research on brain health and ethnic disparities in Alzheimer's disease and related dementia (ADRD) risk, focusing on Arab Americans in metro-Detroit.
Brain Health and Ethnic Disparities in ADRD Risk: The Case of Arab Americans
US · IL
NIH
grant
awarded
#nih-5R01AG070951-04
What they want
Investigate links between immigrant/cultural factors, brain health, and clinical outcomes related to ADRD. This involves obtaining structural MRI and blood-based AD biomarker data from a representative sample of 600 Arab Americans aged 65+ and 298 panel participants from the Social Relations Study (SRS) in the Detroit-Aging and Memory Project (D-AMP). The study will compare these samples to non-Arab Whites in the same geographic area.
Deliverables
- Quantify differences in brain aging among Arab Americans and Whites in metro-Detroit and determine the contribution of brain health to group differences in ADRD
- Determine the contribution of immigrant/cultural factors (e.g., national origin, age of migration) to brain aging among Arab Americans
- Characterize the influence of social relations on brain and cognitive aging among Arab Americans and Whites
Technical requirements
- Structural MRI
- blood-based AD biomarker data
- high-quality ADRD phenotypes and genetic data
