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Developing Human Induced Pluripotent Stem Cell Precision Oncology Models

US National Cancer Institute grant open #nih-2R50CA233164-06A1

Summary

Abstract This proposal was specifically designed to support a dedicated Research Specialist with extensive experience in human induced pluripotent stem cell (hiPSC) engineering to study the cellular and molecular mechanisms underlying the formation and progression of central and peripheral nervous system tumors relevant to the identification of risk assessment and personalized therapeutic strategies. This investigator has longstanding expertise in RASopathy cancer predisposition syndromes, beginning with her doctoral studies focused on generating Cardio-Facial-Cutaneous and Costello Syndrome z

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