Summary
Project Summary Our earlier work identified the neural stem cells (NSC) and intermediate progenitors that generate new neurons and glial cells in the adult mouse brain. These NSCs are regionally specified to produce unique sets of inhibitory interneurons that migrate along the rostral migratory stream (RMS) to the olfactory bulb. Unlike rodents, the adult human brain does not contain an RMS, but this and other migratory streams are present in infants. In young children, we recently found two major streams of migrating young neurons (the ARC and the EC stream) that supply inhibitory cortical in
