Summary
Major Depressive Disorder (MDD) is a prevalent and debilitating disorder, where one-third of this population is treatment-resistant. Depression is characterized by cognitive dysfunction, including deficits in cognitive control, defined as flexible adaptation of cognitive and behavior commensurate with one’s current goals. Application of deep brain stimulation (DBS), a common therapy used for treatment-resistant depression (TRD), has previously shown enhancement in cognitive control during experimental tasks, but therapeutically shown mixed results, and our understanding of the effect of DBS on
