Summary
PROJECT SUMMARY Infections with Human Immunodeficiency Virus (HIV) remain a major global public health concern. The HIV reservoirs are a leading reason for which HIV infection remains without a cure. HIV integrates its viral DNA into the host cell DNA. Cell activation leads to transcription of archived viral information, which can refuel viral replication even in the presence of antiretroviral therapy (ART). This may be problematic when cellular reservoirs of HIV involve cell types that are in continuous functional activation. Research conducted by others and us have shown that pvSMC are susce
