Summary
The NINDS Biospecimen Core Facility processes, stores, maintains, and distributes biological specimens and provides specialized technical research services, including biomarker assays and flow cytometry, for NINDS investigators.
Biospecimen Repository Core
US · IL
National Institute of Neurological Disorders and Stroke (NINDS)
grant
open
#nih-1ZICNS009452-03
What they want
The facility actively stores, maintains, and distributes samples from over 15 NINDS protocols, collects and processes clinical samples from 12 ongoing studies, and has accessioned over 37,838 individual biological specimens. It supports investigators by providing technical research services such as SIMOA (Single Molecule Array) for measuring neurological biomarkers (e.g., Neurofilament Light, TAU protein, cytokines), Seahorse assay for mitochondrial function using clinical blood samples, and multicolor flow cytometry using a Cytek spectral cytometer. The repository also preserves historical samples and plans to offer DNA extraction from peripheral blood and develop a basic website.
Deliverables
- Stored and maintained biological specimens
- Distributed biological specimens
- Processed clinical samples
- SIMOA assay data
- Seahorse assay data
- Flow cytometry research assay support
Technical requirements
- SIMOA (Single Molecule Array) platform
- Seahorse assay for mitochondrial function
- Cytek spectral cytometer for multicolor flow cytometry
- Meticulous record-keeping
- Capability for DNA extraction from peripheral blood (planned)
