Summary
PROJECT SUMMARY The overall objective of this SCORE is to elucidate sex differences in cardiometabolic disease and its risk factors and treatments using genetically modified mouse models, inbred mouse strains, and in vitro or cell-based experiments. However, another important component of the SCORE is to translate findings from model systems to humans. The Human Translational Bioinformatics Core will fulfill this goal by serving as the hub for computational and in silico analyses that translate findings from the three Projects for association and relevance to cardiometabolic traits in humans,