Neural basis of precedence-type sound localization processes

The project will investigate the neural basis of precedence-type sound localization processes, including the Franssen effect, which are critical for auditory perception, speech-in-noise processing, and source location. It will leverage the natural preference of Hyla versicolor females for slow-rise, long-duration (SR-LD) sound pulses. Aim 1 involves behavioral experiments to test if subjects erroneously approach a loudspeaker broadcasting fast-rise, short-duration (FR-SD) pulses when they precede SR-LD pulses. Aim 2 proposes extracellular recordings from single neurons in the anuran inferior colliculus (ICan) to stimuli that elicit the Franssen effect, hypothesizing that FR-SD pulses suppress SR-LD selective neurons. Aim 3 will examine the role of inhibition in the Franssen effect using in vivo whole-cell recordings and analytical methods to understand temporal integration of binaural inputs to the ICan.