Evolutionary Analysis and Comparative Genomics of Protein Superfamilies

The research focuses on the systematic analysis and discovery of biological conflict systems using comparative genomics. Key areas include understanding the diversity of molecular armaments, mechanisms regulating their deployment, and their shared organizational logic. Specific projects involve studying evolutionary connections between prokaryotic and eukaryotic immune systems, the role of the PcdA enzyme in Staphylococcus aureus cell division, and the characterization of the P-type ATPase superfamily in Mg2+ transport. The work aims to uncover new conflict systems, understand immune system evolution, and identify potential biotechnological reagents and therapeutic targets.