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Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)

US National Institutes of Health (NIH) grant open #PAR-25-043
Response due Jan 07, 2028 · 00:00 UTC

Summary

This is a National Institutes of Health (NIH) funding opportunity announcement (FOA) under program announcement number PAR-25-043, soliciting R01 research grant applications. The opportunity focuses on investigating the biological and clinical mechanisms by which bariatric surgery affects cancer risk. Clinical trials are optional under this announcement. The opportunity opened in September 2024 and accepts applications through early January 2028.

What they want

Solicit R01 research grant applications to study the mechanisms by which bariatric (metabolic) surgery influences cancer risk. Research may include observational studies, mechanistic laboratory investigations, and optionally clinical trials. Applicants must address how bariatric surgical procedures alter biological pathways relevant to cancer development or progression.
Technical requirements
  • Research must focus on mechanisms linking bariatric surgery to cancer risk
  • Clinical trials are optional but permissible under this announcement
  • Applications must conform to NIH R01 grant format and requirements

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

  • Opportunity announcement number (PAR-25-043) and multi-year open window (2024–2028) suggest a standing Program Announcement with Referral — typical NIH rolling submission cycle, not a single-award wired solicitation. No single-bidder red flags identified.
  • Extremely long open window (over 3 years) is standard for NIH PAR announcements but may be confusing for those unfamiliar with NIH grant mechanisms.

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Mechanisms that Impact Cancer Risk after B…
Due Jan 07
Onboard ↗