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Clinical and Translational Science Award (UM1 Clinical Trial Optional)

US · MD National Institutes of Health (NIH) grant open #PAR-24-272
Response due Sep 28, 2027 · 00:00 UTC

Summary

The National Institutes of Health (NIH) is soliciting applications for the Clinical and Translational Science Award (CTSA) program under funding opportunity PAR-24-272. This is a UM1 cooperative agreement mechanism where clinical trials are optional. The CTSA program supports institutions in accelerating the translation of laboratory discoveries into treatments for patients, engaging communities in clinical research, and training the next generation of clinical and translational scientists. The opportunity window spans from September 2024 through September 2027, indicating a multi-cycle award opportunity.

What they want

Applicants must propose programs to advance clinical and translational science. Work includes: (1) building and sustaining infrastructure for clinical and translational research; (2) facilitating the translation of basic science discoveries into clinical applications; (3) engaging patients and communities in research; (4) training and developing clinical and translational science workforce; (5) optionally conducting clinical trials as part of the research program. This is a cooperative agreement (UM1), meaning NIH program staff will have substantial involvement in the conduct of the award.
Technical requirements
  • UM1 cooperative agreement mechanism
  • Clinical trials component is optional
  • NIH program staff will have substantial programmatic involvement as a cooperative agreement

How they evaluate

Submission: Electronic submission via Grants.gov federal grants portal

Risks & flags

  • Multi-year open solicitation window (2024–2027) may favor established CTSA hub institutions with existing NIH relationships
  • UM1 cooperative agreement mechanism implies close NIH involvement, which may advantage incumbent awardees familiar with NIH program staff expectations
  • CTSA program historically concentrated among a limited set of large academic medical centers

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Clinical and Translational Science Award (…
Due Sep 28
Onboard