Summary
This project is a prospective, longitudinal clinical study investigating physical activity and bone health in female adolescents recovering from restrictive eating disorders, comparing them to a healthy control group over one year.
A Prospective, Longitudinal Investigation of Physical Activity and Bone Health among Female Adolescents Recovering from Restrictive Eating Disorders
US · IL
NIH
grant
awarded
#nih-1K23HD120665-01
What they want
Dr. Aubrey Armento will conduct a prospective longitudinal clinical study of female adolescents admitted to the Children’s Hospital Colorado Eating Disorder Program (CHCO-EDP) over 1 year of treatment/recovery, compared to a healthy, physically active control group. Specific aims include: 1) examining physical activity participation (measured by a wearable activity monitor) and its association with compulsive exercise and eating disorder behaviors, and 2) determining changes in bone mineral density (BMD) and bone microarchitecture and estimated strength (measured by high resolution peripheral quantitative computed tomography; HR-pQCT) and the impact of weight-bearing physical activity on these bone outcomes. The study aims to inform clinical approaches to physical activity integration and optimization of bone health during ED recovery.
Deliverables
- Data on physical activity participation, compulsive exercise, and eating disorder behaviors
- Data on changes in BMD, bone microarchitecture, and estimated strength
- Findings on the impact of weight-bearing physical activity on bone outcomes
- Experiential training and career development for Dr. Armento in longitudinal clinical studies, HR-pQCT data analysis, and wearable technology monitoring
Technical requirements
- Wearable activity monitor for physical activity measurement
- High resolution peripheral quantitative computed tomography (HR-pQCT) for BMD and bone microarchitecture measurement
Key personnel
- Dr. Aubrey Armento (Lead Investigator)
