Summary
Project Summary: The value of chemical synthesis in health-related research is closely tied to the ability to efficiently generate medicinal agents from readily available materials. This MIRA application seeks to continue our efforts centered on the development of innovative synthetic transformations of fundamental building blocks. The long-term goal of this program is to identify promising new modes of chemical reactivity that facilitate the rapid discovery and development of small molecules for biomedical applications. The overall objective of this application is to develop a diverse set of