Summary
Project Summary Oral disease causes a significant burden on overall health and 3.9 billion people are affected worldwide. Oral diseases such as periodontitis, cancer, tooth loss, craniofacial birth defects and pain all affect growth and maintenance of the oral cavity and oral mucosa. Improving oral wound healing due to diseases, chronic wounding and scarring would greatly affect quality of life. The oral mucosa is primed with wound- activated gene signatures to facilitate the rapid and scarless wound healing. However, the genetic and molecular mechanism underlying this process is still largel