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Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)

US National Institutes of Health (NIH) grant open #PAR-25-244
Response due Nov 16, 2027 · 00:00 UTC

Summary

The National Institutes of Health (NIH) is soliciting basic research proposals focused on cancer health disparities under the R21 exploratory/developmental research grant mechanism. Clinical trials are explicitly not allowed under this funding opportunity. The program aims to advance foundational scientific understanding of the biological, social, and environmental factors that contribute to disparate cancer outcomes across different populations. This is a standing/rolling opportunity open from November 2024 through November 2027.

What they want

Applicants must propose basic (non-clinical-trial) research addressing cancer health disparities. The R21 mechanism supports exploratory and developmental research projects. Work must be oriented toward generating new scientific knowledge about the mechanisms and determinants underlying disparate cancer incidence, mortality, or treatment outcomes among underserved or minority populations. Clinical trials are explicitly excluded from this funding opportunity announcement (FOA).
Technical requirements
  • No clinical trials permitted
  • Must use R21 exploratory/developmental research grant mechanism
  • Research must focus on basic science related to cancer health disparities

How they evaluate

Submission: Grants.gov federal grants portal (PAR-25-244)

Risks & flags

  • No dollar values or award ceiling/floor stated in the source text — budget constraints unknown
  • Rolling close date of nearly 3 years may indicate ongoing broad solicitation with multiple review cycles — applicants should verify specific submission windows on Grants.gov

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541714
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Basic Research in Cancer Health Disparitie…
Due Nov 16
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