Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)

Summary

This federal funding opportunity, issued through Grants.gov, solicits R01 research grant applications for pilot hybrid effectiveness-implementation trials focused on mental health interventions. The mechanism requires a clinical trial component and is aimed at generating early-stage evidence on both the effectiveness of mental health interventions and the strategies for implementing them in real-world settings. Applicants are expected to design studies that simultaneously test clinical outcomes and implementation outcomes. This is a research grant opportunity, not a traditional procurement contract.

What they want

How they evaluate

Risks & flags

• Insufficient source text provided to fully assess wiring or bias — only title and source name were supplied; full FOA text was not included
• Clinical Trial Required designation may limit eligibility to institutions with IRB infrastructure and clinical trial management capacity, narrowing the applicant pool