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Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative UG3/UH3 Clinical Trial Required)

US National Institutes of Health / National Center for Complementary and Integrative Health (NCCIH) grant open #PAR-24-275
Response due Jul 14, 2026 · 00:00 UTC

Summary

The National Center for Complementary and Integrative Health (NCCIH), part of NIH/HHS, is soliciting applications for a Clinical Coordinating Center to support multi-site investigator-initiated clinical trials focused on mind and body interventions. This is a collaborative grant opportunity using the UG3/UH3 phased award mechanism, meaning awardees must first complete a planning/milestone phase (UG3) before advancing to the full trial execution phase (UH3). The opportunity is open for applications from September 2024 through July 2026, indicating a rolling or multi-cycle submission window.

What they want

Applicants must propose and operate a Clinical Coordinating Center (CCC) to support NCCIH-funded multi-site investigator-initiated clinical trials of mind and body interventions. The award mechanism is a Collaborative UG3/UH3 phased grant. The UG3 phase involves planning, protocol development, and milestone achievement; the UH3 phase involves full clinical trial execution. A clinical trial is required as part of the application. The CCC is expected to provide coordination infrastructure across multiple clinical trial sites.
Technical requirements
  • Clinical trial must be included as part of the application
  • Collaborative UG3/UH3 phased award mechanism required
  • Must support multi-site trial infrastructure
  • Must address mind and body interventions as defined by NCCIH

How they evaluate

Submission: Grants.gov federal grants portal (PAR-24-275)

Risks & flags

  • Rolling/long submission window (Sep 2024 – Jul 2026) may indicate niche applicant pool with few competitive bidders
  • UG3/UH3 phased mechanism is highly specialized and may favor institutions with existing NCCIH relationships or prior phased trial infrastructure
  • Focus on 'mind and body interventions' is a narrow scientific domain that limits the eligible applicant pool

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541714
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Offices of Physicians (except Mental Health)
NAICS 621111
US market size
$520B
Typical award
$50K – $25M (BPA)
Typical buyers
VAIHSDoD MHSState Medicaid
Commonly required
Joint CommissionCMS Medicare providerState licensure
Clinical Coordinating Center for NCCIH Mul…
Due Jul 14
Onboard ↗