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Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)

US · US National Institutes of Health (NIH) grant open #PAR-25-298
Response due Jan 07, 2028 · 00:00 UTC

Summary

The NIH Research Enhancement Award Program (REAP), offered under the R15 grant mechanism, supports meritorious research at health professional schools and graduate schools that have not been major recipients of NIH funding. The program aims to expose students in health professions and graduate programs to research and strengthen the research environment of eligible institutions. Clinical trials are explicitly not allowed under this funding opportunity. The award is intended to enhance the research capacity of smaller or less-NIH-funded academic institutions.

What they want

The REAP R15 program funds biomedical and behavioral research projects conducted at eligible health professional schools and graduate schools. Applicants must propose meritorious research that will: (1) support faculty-led research at institutions that have not been major NIH funding recipients; (2) engage students in health professional or graduate programs in active research; and (3) strengthen the institution's research environment. Clinical trials are not permitted under this announcement (PAR-25-298).
Technical requirements
  • Clinical trials are not allowed
  • Applicant institutions must be health professional schools or graduate schools
  • Institutions must not be major recipients of NIH funding
  • Research must involve student participation in health professional or graduate programs
  • Must use R15 grant mechanism

How they evaluate

  • Scientific and technical merit of the proposed research
  • Significance and innovation of the research
  • Approach and methodology
  • Investigator qualifications
  • Environment and institutional support
  • Student involvement in research activities
Submission: Grants.gov electronic submission portal

Eligibility & certifications

SAM registration (System for Award Management) typically required for federal grantsInstitutional eligibility as a health professional school or graduate school with limited NIH funding history

Risks & flags

  • Extremely long open window (over 3 years, Dec 2024–Jan 2028) suggests a rolling/standing program announcement rather than a competitive solicitation — not wired for a single bidder but applicants should note eligibility restrictions on NIH funding history may limit competition to smaller institutions

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541714
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Research Enhancement Award Program (REAP) …
Due Jan 07
Onboard