Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)

Summary

The National Institutes of Health (NIH) is forecasting a funding opportunity for the systematic characterization of genomic variation to assess the effects of individual variants on genome function and phenotype. The mechanism is a UM1 cooperative agreement, explicitly excluding clinical trials. The opportunity is focused on large-scale, coordinated genomic research to understand how specific genetic variants influence biological function and observable traits. As a forecasted opportunity, full programmatic details have not yet been released.

What they want

How they evaluate

Risks & flags

• Forecasted status — full solicitation details not yet available; scope, eligibility, and evaluation criteria cannot be fully assessed
• UM1 mechanism typically implies large, coordinated multi-site projects which may favor established genomics consortia or institutions with prior NIH large-grant experience