MEDICINAL CHEMISTRY CONSULTING SERVICES

The medicinal chemistry Consultant will provide executive (senior scientific)-level Medicinal Chemistry expertise and contribute feedback and guidance on projects to the NIH and to Lead Development Team (LDT) members through video/tele conference and by email. Responsibilities include offering input on project milestones, target product profiles, and testing funnels; providing feedback on chemical structures and processes for SAR; evaluating SAR data weekly or biweekly; evaluating the tractability and IP space of chemical structures; advising, strategically planning, and managing medicinal chemistry programs (hit-to-lead, lead optimization, IND enabling, clinical studies); identifying drug discovery and development challenges and suggesting strategies; collaborating on design of investigative studies; reviewing Medicinal Chemistry sections of regulatory filings; and facilitating LDT discussions. The consultant may also accompany NIH staff on visits to CRO facilities to inspect facilities and prepare trip reports.