Summary
Abstract Failure to detect and treat atherosclerosis in younger adults worsens cardiovascular morbidity and mortality. Current strategies of assigning preventive therapies are not based on screening for atherosclerosis, but rather on short-term risk scores that heavily weight age and leave most at-risk young and middle-aged adults untreated. A new paradigm of screening for and identifying subclinical atherosclerosis via coronary computed tomography angiography (CCTA) is emerging because subclinical atherosclerosis has prognostic superiority over traditional risk scores. However, it is still un