Neuronal mechanisms of image processing in the early visual pathway

The project hypothesizes that myopia results from under-stimulation of ON visual pathways. It will test this by directly measuring neuronal and visual function mediated by ON and OFF pathways in humans with myopia and normal vision. This involves using clinical recording methods like electroretinography and electroencephalography to measure stimulus tuning differences and automated photography to assess ON/OFF stimulation balance in outdoor scenes. New visual tests utilizing head-mounted displays, wearable eye tracking, and electrically tunable lenses will measure ON and OFF pathway-mediated vision, with collected data used to develop a computational model simulating myopia progression in various visual environments.