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A 3D zebrafish microanatomical and gene expression atlas for disease modeling

US NIH Office of the Director grant open #nih-1R24OD037633-01A1

Summary

Project Summary The zebrafish is a vertebrate model organism with significant genetic, cellular, and physiological similarities with humans. Its powerful genetic and imaging tools have allowed us to decipher gene function, embryonic development, and disease mechanisms. Its small size and recent advances in imaging allow the unbiased visualization of phenotypes across all cell types and tissues through adulthood. This creates a unique opportunity for an integrative atlas resource that will allow the interpretation of multi-omic data in the context of the whole organism. The labeled 3D whole-ani

A 3D zebrafish microanatomical and gene ex…
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